Phenotypic Constraints and Phenotypic Hitchhiking in a Promiscuous Enzyme
نویسندگان
چکیده
منابع مشابه
Phenotypic Constraints and Phenotypic Hitchhiking in a Promiscuous Enzyme
Covarying phenotypic traits can limit natural selection’s ability to modify these traits. Most evolutionary studies on trait covariation use the comparative method to study complex traits of multicellular organisms. Simpler traits have the advantage of being amenable to experimental evolution. Here we study such a simple molecular system, the TEM-1 beta-lactamase protein, a promiscuous enzyme t...
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ژورنال
عنوان ژورنال: The Open Evolution Journal
سال: 2012
ISSN: 1874-4044
DOI: 10.2174/1874404401206010014